The fact that my own iterative calculations (via spreadsheet and ) match those of IGT's (displayed on the Wizard's Multi-Strike Poker Deluxe page) gives me a good measure of faith in IGT's calculations (and my own for that matter!).
I realize that I am more likely to find favorable paytables on the 'novelty games' in Reno than here in Carson City - a game like Multi-Strike 16X could pose quite a risk to a smaller casino even in mid-range denominations. I enjoy the playing 4-level Multi-Strike SDDB 8/5 and would thoroughly enjoy playing MS 16X, if any of my local casinos had decent paytables.